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MYP_046007
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Basic Information
Temporin L [F1L,V2L,F5L,F8L,I12W]
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C80H128N20O16
Standard
Sequence
LLQWLSKLLGRWL
Physicochemical Analysis
1626.00 Da
11.00
1.76
1.55
0.1353
0.61
0.64
0.26
90.82
180.00
0.1538
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
595.34
0.22
22.0
18.0
53.0
116.0
4.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0315863 VERIFIED: YES
Provenance & Taxonomy
Rana temporaria [Animal]
8407.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
6 μM
Hemolysis
PaperMangoni ML, Carotenuto A, Auriemma L, et al. Structure-activity relationship, conformational and biological studies of temporin L analogues. J Med Chem. 2011 Mar 10;54(5):1298-1307. doi:10.1021/jm1012853. PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0346526 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Saccharomyces cerevisiae
12 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0362016 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus Cowan 1
6 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0381188 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Bacillus megaterium Bm11
3 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
RECORD: Rec_0392469 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Temporin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Yersinia pseudotuberculosis YPIII
6 μM
MIC
PMID21319749 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21319749/
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