Peptide Database

Peptide NameSLAY-screened peptide P1209

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC74H119N21O21S3

DescriptionStandard

        VTFLRSGRPYMCMSS
    

Molecular Weight1735.06 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)1.72

Net Charge (pH 7.4) 1.50

Charge Density (pH 7.0) 0.1149

GRAVY Index0.11

Hydrophobic Moment 0.52

Boman Index0.01

Instability Index160.03

Aliphatic Index 45.33

Aromaticity 0.1333

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 686.88

LogP -7.46

H-bond Donors 27.0

H-bond Acceptors 26.0

Rotatable Bonds 54.0

Heavy Atoms 119.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0141807 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/