Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC408H615N103O106S9

DescriptionStandard

        MALIRKTFYFLFAVFFILVQLPSGCQAGLDFSQPFPSGEFAVFESCKFSWGKCRKECLENEKPCGNCRLNFLCCRQSI
    

Molecular Weight8947.46 Da

Isoelectric Point (pI)8.48

Net Charge (pH 7.0)2.43

Net Charge (pH 7.4) 2.08

Charge Density (pH 7.0) 0.0312

GRAVY Index0.22

Hydrophobic Moment 0.43

Boman Index0.12

Instability Index49.19

Aliphatic Index 71.28

Aromaticity 0.1667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3349.62

LogP -26.48

H-bond Donors 122.0

H-bond Acceptors 118.0

Rotatable Bonds 291.0

Heavy Atoms 626.0

Ring Count 18.0

Amide Bonds 84.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050018 VERIFIED: NO

Provenance & Taxonomy

OrganismNomascus leucogenys [Animal]

FamilyDefensin

Tax ID61853

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence