Peptide Database

Peptide NameBrevinin-2SN2

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC358H582N90O112S5

DescriptionStandard

        MFTLKKPLLFLFFLGTISLSFCEEERGADEDDGGEMTEEEKRGVLDTLKNVAIGVAKGAGTGVLKALLCQLDKSC
    

Molecular Weight8099.31 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-4.51

Net Charge (pH 7.4) -4.79

Charge Density (pH 7.0) -0.0601

GRAVY Index0.08

Hydrophobic Moment 0.68

Boman Index0.09

Instability Index22.61

Aliphatic Index 94.93

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3246.79

LogP -28.92

H-bond Donors 114.0

H-bond Acceptors 113.0

Rotatable Bonds 282.0

Heavy Atoms 565.0

Ring Count 6.0

Amide Bonds 76.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0130630 VERIFIED: YES

Provenance & Taxonomy

OrganismSylvirana spinulosa [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Candida Cytolytic Hemolytic

RECORD: Rec_0309303 VERIFIED: NO