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MYP_045938
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Basic Information
Brevinin-2SN1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
33 amino acids
C147H261N43O44S2
Standard
Sequence
GLRDKIKNVAIDVAKGAGTGVLKALLCQLDKSC
Physicochemical Analysis
3399.04 Da
9.24
2.74
2.50
0.0830
0.25
0.54
0.05
-0.03
121.21
0.0000
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1425.06
-14.49
51.0
49.0
121.0
236.0
0.0
34.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0033437 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
E.cloacae CGMCC 1.57
400 μM
MIC
PaperIdentification of multiple antimicrobial peptides from the skin of fine-spined frog, Hylarana spinulosa (Ranidae).
RECORD: Rec_0035172 VERIFIED: YES
Provenance & Taxonomy
Amphibia [Animal]
Brevinin
8292
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
27-33
Bio-Activity Profile
Antimicrobial
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
RECORD: Rec_0046609 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic Anti-Gram-positive
Staphylococcus aureus
200 μM
MIC
RECORD: Rec_0110428 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Enterobacter cloacae CGMCC 1.57
400 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
RECORD: Rec_0148817 VERIFIED: YES
Provenance & Taxonomy
Hylarana spinulosa [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
200 μM
MIC
PMID24055160 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24055160/
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