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MYP_045875
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Basic Information
Thiocillin GE2270 (Antibiotic GE2270; Bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
14 amino acids
C52H81N15O19S6
Standard
Sequence
SCNCVCGFCCSCSP
Physicochemical Analysis
1412.68 Da
5.23
-0.60
-0.89
-0.0428
1.01
0.23
0.23
79.80
20.71
0.0714
0.00
375.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
536.61
-9.83
24.0
25.0
40.0
92.0
2.0
14.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0011229 VERIFIED: YES
Provenance & Taxonomy
Planobispora rosea [Bacterium]
Bacteriocin
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPubMed PMID: 1908853 PMID1908853 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1908853/
RECORD: Rec_0196452 VERIFIED: YES
Provenance & Taxonomy
Planobispora rosea [Bacterium]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID1908853 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1908853/
RECORD: Rec_0233585 VERIFIED: YES
Provenance & Taxonomy
Planobispora rosea [other]
Thiocillin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Bacteriocin Anti-Gram-negative Anti-Gram-positive Non-hemolytic
Gram Negative Bacteria and Gram Positive Bacteria
PMID1908853;7647369;16876786;17503407;1880060;7844053;7592050;10625477;16734421 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/1908853/
RECORD: Rec_0238796 VERIFIED: YES
Provenance & Taxonomy
Planobispora rosea [Bacterium]
thiocillin family
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
3-Asn: N4-methylasparagine; 8-Phe: 3-hydroxyphenylalanine
Bio-Activity Profile
Antimicrobial thiocillin family Antibacterial Host defense
PaperPDB 3U6B structural record; X-ray; 2.12 A; chain C/D; residues 1-10
RECORD: Rec_0278055 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 14.3%, T 57.1%, C 28.6% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antibacterial Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/