Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length336 amino acids

Chemical FormulaC1651H2530N432O476S12

DescriptionStandard

        MKGLVRGHVEFNSTLCSLTTSGAVGRREGDDVRLRRVWVHFPPSLGGLPGGGGNGTGTAVPDSTLADANSASQTPEMPLWGAGSRSLFSSLVTYKIDRIAGISYSLVAPSDSETYTEEHIYPPFFSLAHPRSPPFTPPAMALPPDHDHMVYLGISDYFFNTAGLVYQEAGALNMTITDDMIPKKSKFRLTTDFLGTLIPQVAEMFPNMTVQFNVWASSPPHLTMRPAGLIFTPTLDTQAFAVLPNSSLAPLFVLGLVSCSQLWADEGTARWFREAAHLALGGGPLPSLLRTDLPSIAERLQEGFPLPMPKNVQLFNLVLQTHQDFLLFGADVHYSG
    

Molecular Weight36431.14 Da

Isoelectric Point (pI)5.64

Net Charge (pH 7.0)-7.61

Net Charge (pH 7.4) -8.41

Charge Density (pH 7.0) -0.0226

GRAVY Index0.01

Hydrophobic Moment 0.70

Boman Index0.16

Instability Index46.65

Aliphatic Index 84.49

Aromaticity 0.0982

Extinction Coeff. Reduced 39420.00

Extinction Coeff. Oxidized 39545.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0062634 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus dingo [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria