Peptide Database

Peptide NameEndolysin (EC 3.5.1.28) (N-acetylmuramoyl-L-alanine amidase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length151 amino acids

Chemical FormulaC752H1172N214O218S8

DescriptionStandard

        MSKVQFKPRAMTEAIFVHCSATKASMNVGLREIRQWHKEQGWLDVGYHFIIRRDGTIEEGRPVDVVGSHVKDWNSKSVGVCLVGGIDDKGKHEANFTPAQMHSLKEKLADLLDMYPDAEVKAHHDVAPKACPSFNLSRWLKTGELVTSDWG
    

Molecular Weight16955.17 Da

Isoelectric Point (pI)7.09

Net Charge (pH 7.0)0.19

Net Charge (pH 7.4) -0.52

Charge Density (pH 7.0) 0.0013

GRAVY Index-0.43

Hydrophobic Moment 0.75

Boman Index-0.02

Instability Index41.10

Aliphatic Index 75.50

Aromaticity 0.0795

Extinction Coeff. Reduced 30480.00

Extinction Coeff. Oxidized 30605.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6910.39

LogP -64.82

H-bond Donors 242.0

H-bond Acceptors 234.0

Rotatable Bonds 564.0

Heavy Atoms 1192.0

Ring Count 31.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225425 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage 285P [Virus]

FamilyN-acetylmuramoyl-L-alanine amidase 2

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Hydrolase Cytolytic Non-hemolytic