Peptide Database

Peptide NameSLAY-screened peptide P1032

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC93H150N26O33S

DescriptionStandard

        PEFSLSNNSPCSTINALERL
    

Molecular Weight2192.41 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-1.05

Net Charge (pH 7.4) -1.12

Charge Density (pH 7.0) -0.0523

GRAVY Index-0.30

Hydrophobic Moment 0.50

Boman Index-0.01

Instability Index36.39

Aliphatic Index 83.00

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 960.36

LogP -13.11

H-bond Donors 34.0

H-bond Acceptors 33.0

Rotatable Bonds 70.0

Heavy Atoms 153.0

Ring Count 3.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0384769 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/