Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length162 amino acids

Chemical FormulaC786H1249N231O226S3

DescriptionStandard

        MAVITPQQAGGKNVCAFLDMIAYSEGTDNGRQRTNHNGYDVLVGGGLFTGFADHPRKLVALPKLGIKSTAAGRYQLLSRYYDAYKKQLGLKDFSPLSQDLIAIQQIRERRALPLIQAGQFEQAVRQVRNIWASLPGAGYGQHEQKIANLLAAYRNAGGTVAA
    

Molecular Weight17646.93 Da

Isoelectric Point (pI)9.79

Net Charge (pH 7.0)7.75

Net Charge (pH 7.4) 7.34

Charge Density (pH 7.0) 0.0479

GRAVY Index-0.26

Hydrophobic Moment 0.82

Boman Index0.02

Instability Index31.37

Aliphatic Index 89.88

Aromaticity 0.0864

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7406.36

LogP -76.63

H-bond Donors 255.0

H-bond Acceptors 240.0

Rotatable Bonds 588.0

Heavy Atoms 1246.0

Ring Count 24.0

Amide Bonds 182.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0124779 VERIFIED: NO

Provenance & Taxonomy

OrganismEscherichia phage vB_EcoM_ECOO78 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic