Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC407H648N120O123S14

DescriptionStandard

        MKTFSVAVAVAVVLTFICLQESSAASFTEVQELEEPMSNGSPVAADEEMSEESWKMPYASRRWRCRFCCRCCPRMRGCGLCCQRR
    

Molecular Weight9639.14 Da

Isoelectric Point (pI)7.47

Net Charge (pH 7.0)0.43

Net Charge (pH 7.4) 0.07

Charge Density (pH 7.0) 0.0051

GRAVY Index-0.12

Hydrophobic Moment 0.65

Boman Index-0.07

Instability Index95.52

Aliphatic Index 56.24

Aromaticity 0.0824

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3921.63

LogP -42.85

H-bond Donors 149.0

H-bond Acceptors 138.0

Rotatable Bonds 316.0

Heavy Atoms 664.0

Ring Count 13.0

Amide Bonds 88.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035818 VERIFIED: YES

Provenance & Taxonomy

OrganismPagrus major [Animal]

FamilyHepcidin

Tax ID143350

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal

RECORD: Rec_0226765 VERIFIED: NO