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MYP_045693
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Basic Information
Japonicin-1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
14 amino acids
C82H120N16O16S2
Standard
Sequence
FFPIGVFCKIFKTC
Physicochemical Analysis
1650.06 Da
8.90
1.74
1.50
0.1242
1.35
0.51
0.48
6.24
76.43
0.2857
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
505.10
0.06
19.0
20.0
50.0
116.0
5.0
13.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0171168 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0203626 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
Cyclization
8-14
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli
30 μM
MIC
PMID11835990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835990/
RECORD: Rec_0207440 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Japonicin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
8-14
Bio-Activity Profile
Antimicrobial Antibacterial
PaperT. Isaacson et al. / Peptides 23 (2002) 419-425. Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica Evidence URLhttps://www.uniprot.org/uniprotkb/E3WH21/entry
RECORD: Rec_0229559 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Japonicin
Structure & Mods
Linear peptide with a single intramolecular disulfide-stabilized loop [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
8-14
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus
100.0 μM
MIC
PaperT. Isaacson et al. / Peptides 23 (2002) 419-425. Antimicrobial peptides with atypical structural features from the skin of the Japanese brown frog Rana japonica Evidence URLhttps://www.uniprot.org/uniprotkb/P83305/entry
RECORD: Rec_0235306 VERIFIED: YES
Provenance & Taxonomy
Rana japonica [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Anti-Gram-negative Non-hemolytic
Escherichia coli
PMID11835990 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11835990/
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