Peptide Database

Peptide NameSyn-xiamencin-52

Function Ontology

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Venom / Toxin ▸ General toxin ▸ Toxicity

Standard StatusStandard

Sequence Length25 amino acids

Chemical FormulaC144H229N41O33

DescriptionStandard

        AGRQWLTKYLLEELRKRGKKAFIAW
    

Molecular Weight3062.61 Da

Isoelectric Point (pI)10.55

Net Charge (pH 7.0)4.80

Net Charge (pH 7.4) 4.60

Charge Density (pH 7.0) 0.1919

GRAVY Index-0.65

Hydrophobic Moment 0.63

Boman Index-0.18

Instability Index49.23

Aliphatic Index 90.00

Aromaticity 0.1600

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1241.23

LogP -6.09

H-bond Donors 46.0

H-bond Acceptors 38.0

Rotatable Bonds 105.0

Heavy Atoms 218.0

Ring Count 6.0

Amide Bonds 25.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0035537 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic

TargetL. donovani

Activity5.23 μM

MethodIC50

RECORD: Rec_0307446 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyBacteriocin

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antiparasitic Toxicity

TargetTHP-1 cells

Activity>20 μM

MethodCC50