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MYP_045519
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Basic Information
R12-alexa
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
10 amino acids
C60H122N40O11
Standard
Sequence
RRRRRRRRRR
Physicochemical Analysis
1579.87 Da
12.00
9.76
9.56
0.9760
-4.50
0.21
-2.53
524.52
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
944.22
-12.61
41.0
21.0
59.0
111.0
0.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0247003 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Staphylococcus epidermidis ATCC 12228[90-100% Inhibition = 20 microM]
PMID22319541;24243601;26922474 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0251301 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Multifunction
P4-R5 MAG
14 μg/mL
IC50
PaperInfection by CXCR4-Tropic Human Immunodeficiency Virus Type 1 Is Inhibited by the Cationic Cell-Penetrating Peptide Derived from HIV-1 Tat. PMID22319541 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0264716 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Escherichia coli ATCC 25922[90-100% Inhibition = 20-30 microM]
PMID22319541;24243601;26922474 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0280003 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Salmonella enterica subsp. enterica serovar Typhimurium ATCC 14028[90-100% Inhibition = 30 microM]
PMID22319541;24243601;26922474 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
RECORD: Rec_0307189 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
Pseudomonas aeruginosa ATCC 27853[30-40% Inhibition = 20-30 microM]
PMID22319541;24243601;26922474 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22319541/
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