Peptide Database

Peptide NameCycloviolacin O16

Function Ontology

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Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC114H183N33O37S6

DescriptionStandard

        GLPVCGETCVGGTCNTPGCSCSWPVCIR
    

Molecular Weight2800.26 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0106

GRAVY Index0.46

Hydrophobic Moment 0.27

Boman Index0.23

Instability Index31.85

Aliphatic Index 58.93

Aromaticity 0.0357

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1081.88

LogP -15.34

H-bond Donors 43.0

H-bond Acceptors 43.0

Rotatable Bonds 81.0

Heavy Atoms 190.0

Ring Count 5.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191219 VERIFIED: YES

Provenance & Taxonomy

OrganismViola odorata [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)