MYP_045425
Peptide 5
Anticancer
Anticancer
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Cytotoxic anticancer activity
▸
Cytotoxic
Toxicity / Safety
▸
Cytotoxicity
▸
Cytotoxic
Venom / Toxin
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General toxin
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Cytotoxic
not Standard
40 amino acids
-
contains X representing unresolved or non-standard residue
FCYWXXXTKKRPKPFQWFWLXKKLMYPTYLKKFQWAVXHL
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Amino Acid Composition
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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RECORD: Rec_0356800
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bombesin-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Reported in source metadata; exact sites not clearly specified.
Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen
Bio-Activity Profile
Anticancer
MiaPaCa.2
0.1 μM
Inhibition
RECORD: Rec_0371272
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bombesin-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Reported in source metadata; exact sites not clearly specified.
Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen
Bio-Activity Profile
Anticancer
MiaPaCa.2
0.210 μM
ED50
RECORD: Rec_0380316
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bombesin-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Reported in source metadata; exact sites not clearly specified.
Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen
Bio-Activity Profile
Anticancer
MiaPaCa.2
10 μM
Inhibition
RECORD: Rec_0403477
VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Bombesin-derived peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
None
Amidation
Reported in source metadata; exact sites not clearly specified.
Aib = = 1-amino-isobutyric acid, O= Ornithine, Pen=penicillamine, CyLeu=cycloleucine or 1-aminocyclopentane-1-carboxylic acid and disulfide bond between Cys and Pen
Bio-Activity Profile
Anticancer
PTC
0.01 μM
Inhibition
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