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MYP_045317
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Basic Information
Ixosin [H3A,E8K,E13L,S16V], Ixosin-pch-H3A
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
18 amino acids
C97H166N28O22S
Standard
Sequence
GLAKVMRKVLGYLRNVYK
Physicochemical Analysis
2108.59 Da
10.56
4.76
4.54
0.2642
0.01
0.76
-0.07
4.47
118.89
0.1111
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
843.43
-4.53
31.0
28.0
73.0
148.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0003983 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0180769 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human embryonic kidney HEK293 cells (23% Killing at 4 microM
293 μM
Hemolysis
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0236276 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Escherichia coli MG1655
02-4 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0263333 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa PAO1
8 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
RECORD: Rec_0284995 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans
16-32 μM
MIC
PMID27622949 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27622949/
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