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MYP_045244
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Metabolic ▸ Uric acid metabolism ▸ Hypouricemic activity
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
3 amino acids
C18H24N4O4
Standard
Sequence
GVW
Physicochemical Analysis
360.41 Da
5.53
-0.24
-0.44
-0.0800
0.97
0.31
0.79
6.67
96.67
0.3333
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
137.31
0.38
5.0
4.0
8.0
26.0
2.0
2.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0311570 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
3.62 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
RECORD: Rec_0312877 VERIFIED: YES
Provenance & Taxonomy
Pachymedusa dacnicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Enzyme inhibitory ACE inhibitory
Angiotensin-converting enzyme
2400 μM
IC50
RECORD: Rec_0316587 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 0.0%, C 100.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihypertensive
PaperAHTPDB: a comprehensive platform for analysis and presentation of antihypertensive peptides PMID25392419 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25392419/
RECORD: Rec_0336350 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive
Spontaneously hypertensive rat (SHR)
22 mmHg
SBP decrease
PaperAntihypertensive peptides from food proteins: a review. PMID22249830 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22249830/
RECORD: Rec_0389374 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
240.0
IC50
PaperChen G. W., Tsai J. S., Pan B. S.. Purification of angiotensin I-converting inhibitory peptides and antihypertensive effect of milk produced by protease-facilitate lactic fermentation. Int. Dairy J., 2007, 17, 641-647.
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