Peptide Database

Peptide NamepAntpHD (3Pro)

Function Ontology

Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide

Delivery / Targeting ▸ Drug delivery vehicle

Standard StatusStandard

Sequence Length16 amino acids

Chemical FormulaC103H161N33O19

DescriptionStandard

        RQPKIWFPNRRKPWKK
    

Molecular Weight2165.59 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)6.76

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.4223

GRAVY Index-2.21

Hydrophobic Moment 0.29

Boman Index-0.67

Instability Index69.47

Aliphatic Index 24.38

Aromaticity 0.1875

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 880.99

LogP -4.63

H-bond Donors 31.0

H-bond Acceptors 26.0

Rotatable Bonds 69.0

Heavy Atoms 155.0

Ring Count 8.0

Amide Bonds 17.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006528 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyPenetratin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

C-TermAmidation

Other ModsN-term detail: Biotinylation

Bio-Activity Profile

Function

Cell-penetrating peptide

TargetCortical striatal cells

MethodCellular uptake assay

RECORD: Rec_0237821 VERIFIED: YES

Provenance & Taxonomy

OrganismDrosophila melanogaster [Animal]

FamilyPenetratin

Tax ID7227

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

C-TermAmidation

Bio-Activity Profile

Function

Cell-penetrating peptide Cargo delivery

RECORD: Rec_0367996 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBiotinylation

C-TermAmidation

Bio-Activity Profile

Function

Drug Delivery Vehicle Cell-penetrating peptide