Peptide Database

Peptide NameAntagonist D [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-SP

Function Ontology

Anticancer

Standard StatusStandard

Sequence Length22 amino acids

Chemical FormulaC142H203N35O26S

DescriptionStandard

        RPKPFQWFWLLRPKPQQFFGLM
    

Molecular Weight2848.41 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.76

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1708

GRAVY Index-0.52

Hydrophobic Moment 0.28

Boman Index0.03

Instability Index57.40

Aliphatic Index 53.18

Aromaticity 0.2727

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11000.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 975.95

LogP -0.87

H-bond Donors 32.0

H-bond Acceptors 31.0

Rotatable Bonds 85.0

Heavy Atoms 204.0

Ring Count 12.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0334122 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilySubstance P

Structure & Mods

Configlinear peptide [Linear]

Chiralitymixed L/D amino-acid peptide [Mixed]

N-TermNone

C-TermNone

Other ModsD-residue notation at positions 1, 5, 7, 9; Mixed L/D stereochemistry with D-annotated positions 1, 5, 7, 9

Bio-Activity Profile

Function

Anticancer

MethodRP-HPLC and Electrochemical Detection

Half-LifeMouse liver homogenate, in vitro; 16560 s