Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length52 amino acids

Chemical FormulaC229H398N66O75S8

DescriptionStandard

        MSDCDLNVKVSSTALKIQPRTTSISLCTSGCNTRILMACLLEIATCGCHISK
    

Molecular Weight5532.53 Da

Isoelectric Point (pI)8.30

Net Charge (pH 7.0)1.53

Net Charge (pH 7.4) 1.17

Charge Density (pH 7.0) 0.0294

GRAVY Index0.40

Hydrophobic Moment 0.44

Boman Index0.09

Instability Index63.76

Aliphatic Index 99.42

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2273.33

LogP -29.20

H-bond Donors 87.0

H-bond Acceptors 86.0

Rotatable Bonds 187.0

Heavy Atoms 378.0

Ring Count 2.0

Amide Bonds 54.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0387468 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus laudensis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria