Peptide Database

Peptide Namebeta-Defensin, DEFB14

Function Ontology

Antimicrobial

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC176H305N57O55S6

DescriptionStandard

        DRCTKRYGRCKRDCLESEKQIDICSLPRKICCTEKL
    

Molecular Weight4292.04 Da

Isoelectric Point (pI)8.89

Net Charge (pH 7.0)3.71

Net Charge (pH 7.4) 3.40

Charge Density (pH 7.0) 0.1030

GRAVY Index-0.91

Hydrophobic Moment 0.70

Boman Index-0.46

Instability Index65.90

Aliphatic Index 65.00

Aromaticity 0.0278

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1865.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1880.67

LogP -20.70

H-bond Donors 74.0

H-bond Acceptors 65.0

Rotatable Bonds 152.0

Heavy Atoms 294.0

Ring Count 2.0

Amide Bonds 36.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0351199 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyDefensin

Tax ID9606

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide3-31; 10-24; 14-32

Bio-Activity Profile

Function

Antimicrobial