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MYP_045140
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Basic Information
R8
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
9 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XRRRRRRRR
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0126598 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Polyarginine
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Fluorescein/FITC labeling
Amidation
B, Beta-Alanine
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25654426 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25654426/
RECORD: Rec_0132913 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Contains non-standard or unspecified residue(s): X; Conjugate type: amide; Conjugated small molecule: (8S,10S)-10-[(3-amino-2,3,6-trideoxy-¦Á-L-lyxo-hexopyranosyl)oxy]-8-(1-hydrazonoethyl)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-Naphthacenedione
Bio-Activity Profile
Anticancer
PaperNew daunomycin¨Coligoarginine conjugates: Synthesis, characterization, and effect on human leukemia and human hepatoma cells Evidence URLhttps://doi.org/10.1002/bip.21264
RECORD: Rec_0161299 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
FITC
Amidation
X=Beta-Alanine
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID25654426 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25654426/
RECORD: Rec_0185088 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Source entry describes small-molecule/peptide conjugation at one terminus; exact terminus not explicitly assigned in source metadata
Contains non-standard or unspecified residue(s): X; Conjugate type: amide; Conjugated small molecule: Phenytoin
Bio-Activity Profile
-
PaperSynthesis and assessment of a novel peptide conjugate to deliver phenytoin for wound repair. Journal of Drug Delivery Science and Technology. 2007 Evidence URLhttps://doi.org/10.1016/s1773-2247(07
RECORD: Rec_0201993 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
FITC
Amidation
X=Beta-Alanine
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID25654426 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25654426/
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