Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC460H728N128O135S8

DescriptionStandard

        MRTLVILAVILLVALQAQAEPLQARTDEDTAAQEQIPADNPEVVVSFAWDESLAPKNSGLRKNMACYCRIPACLAGERRYGTCYYQGRIWAFCC
    

Molecular Weight10468.00 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-1.54

Net Charge (pH 7.4) -1.87

Charge Density (pH 7.0) -0.0164

GRAVY Index0.04

Hydrophobic Moment 0.53

Boman Index0.06

Instability Index52.10

Aliphatic Index 91.49

Aromaticity 0.0851

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4225.93

LogP -38.88

H-bond Donors 151.0

H-bond Acceptors 142.0

Rotatable Bonds 337.0

Heavy Atoms 731.0

Ring Count 15.0

Amide Bonds 102.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0141629 VERIFIED: NO

Provenance & Taxonomy

OrganismColobus angolensis palliatus [Animal]

FamilyDefensin

Tax ID336983

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence