Peptide Database

Peptide NameCycloviolacin VY1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length24 amino acids

Chemical FormulaC108H169N29O32S6

DescriptionStandard

        CGESCVWIPCISSAWGCSCKNKIC
    

Molecular Weight2578.06 Da

Isoelectric Point (pI)7.77

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.41

Charge Density (pH 7.0) 0.0292

GRAVY Index0.51

Hydrophobic Moment 0.31

Boman Index0.21

Instability Index44.18

Aliphatic Index 65.00

Aromaticity 0.0833

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 968.76

LogP -10.87

H-bond Donors 40.0

H-bond Acceptors 39.0

Rotatable Bonds 80.0

Heavy Atoms 175.0

Ring Count 5.0

Amide Bonds 24.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0049256 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)