Peptide Database

Peptide NameMacromomycin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length146 amino acids

Chemical FormulaC634H1028N178O206S4

DescriptionStandard

        MTVKNKLGLVTRLGAAAAIAAGLAVAVQPSAMAASPVVSVSPVNGLADGQQVTVAASGLTPNTVFHVGQCAFVEPSVYGCDATTSKDVTSDAQGKLNTTLVVHSSFQAVVGADRHVWGTVDAKTTQTQVGLGSDTGEGGGQLISFK
    

Molecular Weight14568.27 Da

Isoelectric Point (pI)6.24

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.67

Charge Density (pH 7.0) -0.0086

GRAVY Index0.27

Hydrophobic Moment 0.47

Boman Index0.20

Instability Index13.48

Aliphatic Index 89.45

Aromaticity 0.0411

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6082.93

LogP -79.89

H-bond Donors 210.0

H-bond Acceptors 212.0

Rotatable Bonds 472.0

Heavy Atoms 1022.0

Ring Count 15.0

Amide Bonds 158.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0288940 VERIFIED: NO

Provenance & Taxonomy

OrganismStreptomyces bungoensis [Bacterium]

FamilyNeocarzinostatin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Non-hemolytic Non-ribosomal