Peptide Database

Peptide NameNatriuretic peptide PaNP-d

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC142H231N39O50S3

DescriptionStandard

        SGSKTAEIDDGCFGLPLDPIGSTSGMGCRSVPKP
    

Molecular Weight3380.78 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-1.56

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0457

GRAVY Index-0.24

Hydrophobic Moment 0.41

Boman Index0.07

Instability Index37.41

Aliphatic Index 57.35

Aromaticity 0.0294

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1393.21

LogP -19.54

H-bond Donors 49.0

H-bond Acceptors 52.0

Rotatable Bonds 107.0

Heavy Atoms 234.0

Ring Count 5.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0050091 VERIFIED: YES

Provenance & Taxonomy

OrganismPseudechis australis [Animal]

FamilyNatriuretic peptide PaNP

Tax ID8670

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour