Peptide Database

Peptide NameCcl (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length437 amino acids

Chemical FormulaC2108H3465N617O629S10

DescriptionStandard

        MLAALKGPFKFGLWGIAIYGVLPSEIAKDDPKMMSKIMTSLPADAVTETPASTLPLDQATVRVRQRVVDVVKDERQHIAVVAGRPMSVPVVDAKPTKRPGVFSVSIPGLPSLQVSVPKGVPTAKAPPKGIVAEKGDSRPAGFTAGGNSREAVIRFPKETGQKPVYVSVTDVLTPAQVKQRQEEEKRRQQAWDAAHPEEGLKRDYDKAKAELDAEDKNIATLNSRIASTEKALPGARAAVQEADKKVKEAEANKDDFVTYNPPHEYGSGWQDQVRYLDKDIQNQNAKLKAAQASLNAMNESLSRDKAALPGAMESRKQKEKKAKDAENKLNEEKKKPRKGAKDYGHDYHPAPKTEDIKGLGDLKKVHLKHQCREVEVGVNAGLVIKAVRFMNGTPSTVSLKGIVPVMANTSGHLILKRVSKLKVRIRKGETLKNIFKR
    

Molecular Weight47837.47 Da

Isoelectric Point (pI)9.75

Net Charge (pH 7.0)24.23

Net Charge (pH 7.4) 23.44

Charge Density (pH 7.0) 0.0555

GRAVY Index-0.62

Hydrophobic Moment 0.65

Boman Index-0.13

Instability Index37.84

Aliphatic Index 78.58

Aromaticity 0.0435

Extinction Coeff. Reduced 28420.00

Extinction Coeff. Oxidized 28420.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0373310 VERIFIED: NO

Provenance & Taxonomy

OrganismKlebsiella pneumoniae [Bacterium]

FamilyColicin/Bacteriocin

Tax ID573

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence