Peptide Database

Peptide NamePancreatic hormone

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide Y family

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length36 amino acids

Chemical FormulaC186H287N51O56S2

DescriptionStandard

        APLEPVYPGDDATPEQMAQYAAELRRYINMLTRPRY
    

Molecular Weight4197.71 Da

Isoelectric Point (pI)4.94

Net Charge (pH 7.0)-1.20

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0333

GRAVY Index-0.78

Hydrophobic Moment 0.84

Boman Index-0.13

Instability Index65.52

Aliphatic Index 65.28

Aromaticity 0.1111

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1722.62

LogP -14.47

H-bond Donors 58.0

H-bond Acceptors 57.0

Rotatable Bonds 128.0

Heavy Atoms 295.0

Ring Count 9.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346017 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyPancreatic hormone

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Receptor modulation Feeding regulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

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