Peptide Database

Peptide NameS11

Function Ontology

Immunology ▸ Cytokine / receptor signaling modulation ▸ TLR inhibition

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Immunology ▸ Inflammation modulation ▸ Anti-inflammatory

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC171H288N62O39S2

DescriptionStandard

        EMFTILEEYFMYRGLLGLRIRRRRRRRRR
    

Molecular Weight3900.64 Da

Isoelectric Point (pI)11.92

Net Charge (pH 7.0)7.84

Net Charge (pH 7.4) 7.66

Charge Density (pH 7.0) 0.2704

GRAVY Index-1.05

Hydrophobic Moment 0.47

Boman Index-0.62

Instability Index191.60

Aliphatic Index 80.69

Aromaticity 0.1379

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1731.61

LogP -12.73

H-bond Donors 69.0

H-bond Acceptors 49.0

Rotatable Bonds 137.0

Heavy Atoms 274.0

Ring Count 4.0

Amide Bonds 28.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0146048 VERIFIED: YES

Provenance & Taxonomy

OrganismOrthopoxvirus vaccinia [Virus]

FamilyP13/A52R-derived

Tax ID10245.0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Immunomodulatory Anti-inflammatory TLR inhibitor

TargetCpG- or LPS-stimulated RAW264.7 macrophage assays