Peptide Database

Peptide NameAntimicrobial peptide HsAp1 (HsAp) (Non-disulfide-bridged peptide 3.3) (NDBP-3.3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC363H633N109O106S4

DescriptionStandard

        MSRRVILTLVLVTILVKTMAGMESKKVETTDEIKKRSGTSEKERESGRLLGVVKRLIVCFRSPFPGRRAISEQT
    

Molecular Weight8348.84 Da

Isoelectric Point (pI)10.63

Net Charge (pH 7.0)7.50

Net Charge (pH 7.4) 7.25

Charge Density (pH 7.0) 0.1014

GRAVY Index-0.20

Hydrophobic Moment 0.70

Boman Index-0.14

Instability Index81.69

Aliphatic Index 97.30

Aromaticity 0.0270

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3533.99

LogP -35.85

H-bond Donors 131.0

H-bond Acceptors 118.0

Rotatable Bonds 295.0

Heavy Atoms 582.0

Ring Count 4.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0269112 VERIFIED: YES

Provenance & Taxonomy

OrganismHeterometrus spinifer [Animal]

FamilyNDBP

Structure & Mods

Confignon-disulfide-bridged amphipathic peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Anti-Gram-negative Cytolytic Hemolytic

TargetCandida tropicalis