Peptide Database

Peptide NameAlpha-melanocyte-stimulating hormone

Function Ontology

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Neuromodulation

Standard StatusStandard

Sequence Length12 amino acids

Chemical FormulaC72H101N19O17S

DescriptionStandard

        SYMEHFRWGKPV
    

Molecular Weight1536.75 Da

Isoelectric Point (pI)8.33

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) 0.29

Charge Density (pH 7.0) 0.0457

GRAVY Index-0.93

Hydrophobic Moment 0.41

Boman Index-0.06

Instability Index72.64

Aliphatic Index 24.17

Aromaticity 0.2500

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 584.78

LogP -2.59

H-bond Donors 21.0

H-bond Acceptors 20.0

Rotatable Bonds 46.0

Heavy Atoms 109.0

Ring Count 6.0

Amide Bonds 11.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0297674 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyOpioid

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Opioid Analgesic Neuromodulator

RECORD: Rec_0404807 VERIFIED: YES