Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length46 amino acids

Chemical FormulaC216H364N56O70S5

DescriptionStandard

        MAKLDDFDLDIVVKKQDNIVQPNITSKSLCTPGCITGILMCLTQNS
    

Molecular Weight5025.86 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-1.53

Net Charge (pH 7.4) -1.80

Charge Density (pH 7.0) -0.0332

GRAVY Index0.15

Hydrophobic Moment 0.47

Boman Index0.10

Instability Index50.09

Aliphatic Index 105.87

Aromaticity 0.0217

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2045.97

LogP -21.71

H-bond Donors 70.0

H-bond Acceptors 74.0

Rotatable Bonds 171.0

Heavy Atoms 347.0

Ring Count 3.0

Amide Bonds 51.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0416958 VERIFIED: NO

Provenance & Taxonomy

OrganismGeobacillus sp. LEMMY01 [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria