Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC450H726N134O142S9

DescriptionStandard

        MRTFTLLIAFLVALQTQAEPLQRRAEEVLDQEQLGEDDQDMSISFGGDESSALQDAGERCLTCYCRLRGCGIGERLIGYCRYRNVIYRLCCRA
    

Molecular Weight10573.98 Da

Isoelectric Point (pI)4.88

Net Charge (pH 7.0)-3.54

Net Charge (pH 7.4) -3.89

Charge Density (pH 7.0) -0.0381

GRAVY Index-0.21

Hydrophobic Moment 0.65

Boman Index-0.08

Instability Index48.25

Aliphatic Index 88.17

Aromaticity 0.0753

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4522.31

LogP -47.13

H-bond Donors 167.0

H-bond Acceptors 148.0

Rotatable Bonds 359.0

Heavy Atoms 735.0

Ring Count 8.0

Amide Bonds 100.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0333733 VERIFIED: NO

Provenance & Taxonomy

OrganismPeromyscus maniculatus bairdii [Animal]

FamilyDefensin

Tax ID230844

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal