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MYP_044854
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Basic Information
TCTP-CPP 20
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
12 amino acids
C71H115N19O14S
Standard
Sequence
MIIFRIAAYHKK
Physicochemical Analysis
1490.86 Da
10.29
2.58
2.31
0.2154
0.42
0.45
0.13
39.18
114.17
0.1667
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
546.27
-0.66
20.0
19.0
50.0
105.0
3.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019172 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
TCTP
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
RECORD: Rec_0062666 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
TCTP
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
N-term detail: FITC labeling
Bio-Activity Profile
Cell-penetrating peptide
HeLa
Fluorescence-based uptake assay
PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
RECORD: Rec_0133627 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
FITC
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. Eur J Pharm Sci. 2011 May 18;43(1-2):25-31. doi: 10.1016/j.ejps.2011.03.007. PMID: 21440624. PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
RECORD: Rec_0253071 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
FITC
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PaperDesign and evaluation of variants of the protein transduction domain originated from translationally controlled tumor protein. Eur J Pharm Sci. 2011 May 18;43(1-2):25-31. doi: 10.1016/j.ejps.2011.03.007. PMID: 21440624. PMID21440624 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21440624/
RECORD: Rec_0266128 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
Amidation
Bio-Activity Profile
Drug Delivery Vehicle Cell-penetrating peptide
PaperCPPsite: a curated database of cell penetrating peptides PMID22403286 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22403286/
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