Peptide Database

Peptide Nameα-CGRP-(8-37) (human)

Function Ontology

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Neurological / Signaling ▸ Receptor modulation ▸ Agonist

Neurological / Signaling ▸ Receptor modulation ▸ Antagonist

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC139H229N43O39

DescriptionStandard

        VTHRLAGLLSRSGGVVKNNFVPTNVGSKAF
    

Molecular Weight3126.57 Da

Isoelectric Point (pI)12.00

Net Charge (pH 7.0)3.82

Net Charge (pH 7.4) 3.55

Charge Density (pH 7.0) 0.1273

GRAVY Index0.14

Hydrophobic Moment 0.59

Boman Index0.09

Instability Index24.63

Aliphatic Index 94.00

Aromaticity 0.0667

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1333.37

LogP -16.45

H-bond Donors 47.0

H-bond Acceptors 44.0

Rotatable Bonds 102.0

Heavy Atoms 221.0

Ring Count 4.0

Amide Bonds 32.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0156047 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyGtoPdb peptide ligand

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Receptor antagonist Vasoactive Signaling peptide

TargetAM1 receptor (Human); AM2 receptor (Human); AMY1 receptor (Human)