Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length108 amino acids

Chemical FormulaC511H837N141O148S13

DescriptionStandard

        MKSLLFTLAVFMLLAQLVSGNWYVKKCLNDVGICKKKCKPGEMHIKNGWATCGKQRDCCVPADRRANYPAFCVQTKTTRTSTVTATTTLMVTTASMSSMAPTPVSPTG
    

Molecular Weight11740.81 Da

Isoelectric Point (pI)9.60

Net Charge (pH 7.0)9.51

Net Charge (pH 7.4) 9.12

Charge Density (pH 7.0) 0.0881

GRAVY Index-0.00

Hydrophobic Moment 0.46

Boman Index0.05

Instability Index36.24

Aliphatic Index 68.61

Aromaticity 0.0648

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4628.69

LogP -51.70

H-bond Donors 170.0

H-bond Acceptors 172.0

Rotatable Bonds 383.0

Heavy Atoms 813.0

Ring Count 16.0

Amide Bonds 114.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0197756 VERIFIED: NO

Provenance & Taxonomy

OrganismPan paniscus [Animal]

FamilyDefensin

Tax ID9597

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence