Peptide Database

Peptide NameNeutrophil beta-defensin 12 (Fragment)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length60 amino acids

Chemical FormulaC285H472N86O69S8

DescriptionStandard

        MRLHHLLLALLFLVLSAASGISGPLSCGRNGGVCIPIRCPVPMRQIGTCFGRPVKCCRSW
    

Molecular Weight6463.85 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)6.61

Net Charge (pH 7.4) 6.21

Charge Density (pH 7.0) 0.1102

GRAVY Index0.64

Hydrophobic Moment 0.69

Boman Index0.19

Instability Index35.90

Aliphatic Index 108.83

Aromaticity 0.0500

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2414.40

LogP -21.35

H-bond Donors 92.0

H-bond Acceptors 86.0

Rotatable Bonds 205.0

Heavy Atoms 448.0

Ring Count 11.0

Amide Bonds 61.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0057039 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Tax ID9913

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function