Peptide Database

Peptide NameGirentuximab

Function Ontology

Anticancer

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Standard StatusStandard

Sequence Length449 amino acids

Chemical FormulaC2195H3416N580O673S16

DescriptionStandard

        DVKLVESGGGLVKLGGSLKLSCAASGFTFSNYYMSWVRQTPEKRLELVAAINSDGGITYYLDTVKGRFTISRDNAKNTLYLQMSSLKSEDTALFYCARHRSGYFSMDYWGQGTSVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPVTVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVEPKSCDKTHTCPPCPAPELLGGPSVFLFPPKPKDTLMISRTPEVTCVVVDVSHEDPEVKFNWYVDGVEVHNAKTKPREEQYNSTYRVVSVLTVLHQDWLNGKEYKCKVSNKALPAPIEKTISKAKGQPREPQVYTLPPSRDELTKNQVSLTCLVKGFYPSDIAVEWESNGQPENNYKTTPPVLDSDGSFFLYSKLTVDKSRWQQGNVFSCSVMHEALHNHYTQKSLSLSPGK
    

Molecular Weight49211.13 Da

Isoelectric Point (pI)8.68

Net Charge (pH 7.0)7.55

Net Charge (pH 7.4) 6.55

Charge Density (pH 7.0) 0.0168

GRAVY Index-0.37

Hydrophobic Moment 0.52

Boman Index0.01

Instability Index46.29

Aliphatic Index 72.18

Aromaticity 0.0935

Extinction Coeff. Reduced 68300.00

Extinction Coeff. Oxidized 68925.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0219623 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]; Mus musculus [Animal]

FamilyMonoclonal antibody

Tax ID9606;10090

Structure & Mods

Configlinear peptide/protein therapeutic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anticancer Immunomodulatory

RECORD: Rec_0219736 VERIFIED: NO