Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC983H1557N265O268S9

DescriptionStandard

        PTTPPMAHEPMLLLAVTEFVANSAAFTYFTAGALRRNISNDMLPRRFPIQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCHPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNILGGTVRLTGLVPDPELAQTPLPVLCQAQGLPVPQVKRLETLLKFGLWLFGVPRANSKCYSCPVP
    

Molecular Weight21664.08 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.29

Net Charge (pH 7.4) 3.94

Charge Density (pH 7.0) 0.0219

GRAVY Index0.04

Hydrophobic Moment 0.54

Boman Index0.11

Instability Index58.12

Aliphatic Index 95.05

Aromaticity 0.0765

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8356.38

LogP -102.59

H-bond Donors 284.0

H-bond Acceptors 285.0

Rotatable Bonds 678.0

Heavy Atoms 1525.0

Ring Count 44.0

Amide Bonds 213.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084933 VERIFIED: NO

Provenance & Taxonomy

OrganismVidua macroura [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria