Peptide Database

Peptide NamePhylloseptin-H5 (PLS-H5) (Phylloseptin-7) (PS-7)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC337H535N85O107S2

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEEEKRETEEEENEQEDDDKSEEKRFLSLIPHAINAVSAIAKHFG
    

Molecular Weight7553.49 Da

Isoelectric Point (pI)4.68

Net Charge (pH 7.0)-7.30

Net Charge (pH 7.4) -7.67

Charge Density (pH 7.0) -0.1107

GRAVY Index-0.27

Hydrophobic Moment 0.66

Boman Index-0.01

Instability Index61.24

Aliphatic Index 97.58

Aromaticity 0.0758

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3113.69

LogP -25.37

H-bond Donors 106.0

H-bond Acceptors 104.0

Rotatable Bonds 265.0

Heavy Atoms 531.0

Ring Count 8.0

Amide Bonds 68.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180313 VERIFIED: YES

Provenance & Taxonomy

OrganismPithecopus hypochondrialis [Animal]

FamilyPhylloseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Hemolytic

TargetEscherichia coli (Gram-negative)

RECORD: Rec_0292991 VERIFIED: YES