Peptide Database

Peptide NameNL9-W3A

Function Ontology

Antimicrobial

Antiviral

Antiviral ▸ Anti-HIV ▸ Anti-HIV-1

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Enzyme modulation ▸ Enzyme inhibition ▸ Integrase inhibition

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC56H82N14O15S

DescriptionStandard

        ACAWAGIKQEF
    

Molecular Weight1223.40 Da

Isoelectric Point (pI)6.04

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0193

GRAVY Index0.27

Hydrophobic Moment 0.25

Boman Index0.27

Instability Index58.94

Aliphatic Index 62.73

Aromaticity 0.1818

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 476.52

LogP -2.86

H-bond Donors 17.0

H-bond Acceptors 16.0

Rotatable Bonds 38.0

Heavy Atoms 86.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0404497 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetHIV-1 integrase

Activity33±6 μM

MethodIC50

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