MYP_044669
Basic Information
Insulin-like growth factor I
Hormonal / Endocrine Hormone peptide
Metabolic
Neurological / Signaling Neuromodulation
Neurological / Signaling Neuropeptide activity Neuropeptide
Regulatory peptide Biological modulation
Regulatory peptide Biological regulation
Standard
70 amino acids
C329H516N94O101S7
Standard
Sequence
GPETLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKAAKSA
Physicochemical Analysis
7628.64 Da
7.76
0.71
0.40
0.0101
-0.23
0.46
-0.04
65.57
61.43
0.1000
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3135.72
-35.29
116.0
109.0
247.0
531.0
11.0
72.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050100 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Insulin-like growth factor
9940
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0058907 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Insulin
9940
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
RECORD: Rec_0095414 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Insulin-like growth factor
9940
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
integrins and subsequent ternary complex formation with integrins and IGFR1 are essential for IGF1 signaling
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour
RECORD: Rec_0300904 VERIFIED: YES
Provenance & Taxonomy
Ovis aries [Animal]
Insulin-like growth factor
9940
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
6-48; 18-61; 47-52
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Growth regulation Development regulation Receptor modulation
bone-derived osteoblastic (PyMS) cells
Mammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour