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MYP_044663
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Basic Information
Frenatin 2.1S
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
16 amino acids
C70H123N19O18
Standard
Sequence
GLVGTLLGHIGKAILG
Physicochemical Analysis
1518.84 Da
8.76
0.85
0.59
0.0529
1.27
0.50
0.57
32.96
170.62
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
574.75
-3.74
20.0
20.0
51.0
107.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0000096 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Xanthomonas arboricola pv. Pruni
50 μM
MIC
PMID30508634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508634/
RECORD: Rec_0015641 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
A549
>100 μM
LC50
PMID24704757 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24704757/
RECORD: Rec_0019394 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer
RECORD: Rec_0020174 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID24704757 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24704757/
RECORD: Rec_0035120 VERIFIED: YES
Provenance & Taxonomy
Sphaenorhynchus lacteus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Hemolytic
Horse blood cells
375 μM
Hemolysis
PMID30508634 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30508634/
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