Peptide Database

Peptide NameDefensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC370H587N113O115S7

DescriptionStandard

        MAAPVEDEFEPLEHPETEGRSDRHRRVTCDLLSFKGQINDSACAANCITLGKAGGHCKDGVCICRKTTFKNLWDKRFG
    

Molecular Weight8682.76 Da

Isoelectric Point (pI)6.80

Net Charge (pH 7.0)-0.28

Net Charge (pH 7.4) -0.76

Charge Density (pH 7.0) -0.0036

GRAVY Index-0.59

Hydrophobic Moment 0.52

Boman Index-0.14

Instability Index51.55

Aliphatic Index 58.85

Aromaticity 0.0641

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3688.80

LogP -41.79

H-bond Donors 134.0

H-bond Acceptors 125.0

Rotatable Bonds 291.0

Heavy Atoms 605.0

Ring Count 12.0

Amide Bonds 81.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0299695 VERIFIED: YES

Provenance & Taxonomy

OrganismApis andreniformis [Animal]

FamilyDefensin

Tax ID7464

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal