Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC426H676N114O114S11

DescriptionStandard

        MSHVELGMFYTVLIPVLILIFKMYFVLNLGCQAGLEFSEPFPSGRFAVCESCKLGRGKCRKECLENEKPDGSCRLNFLCCRQRV
    

Molecular Weight9571.33 Da

Isoelectric Point (pI)8.47

Net Charge (pH 7.0)2.52

Net Charge (pH 7.4) 2.12

Charge Density (pH 7.0) 0.0300

GRAVY Index0.21

Hydrophobic Moment 0.46

Boman Index0.07

Instability Index50.96

Aliphatic Index 88.10

Aromaticity 0.1071

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3649.33

LogP -28.79

H-bond Donors 134.0

H-bond Acceptors 129.0

Rotatable Bonds 319.0

Heavy Atoms 665.0

Ring Count 14.0

Amide Bonds 88.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0074906 VERIFIED: NO

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence