Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC228H369N59O78S4

DescriptionStandard

        MSKVELEALKSINDLSDEELANIAGGGDGVVKTATSECYLGTFAFACCLAR
    

Molecular Weight5312.98 Da

Isoelectric Point (pI)4.33

Net Charge (pH 7.0)-4.52

Net Charge (pH 7.4) -4.79

Charge Density (pH 7.0) -0.0885

GRAVY Index0.24

Hydrophobic Moment 0.60

Boman Index0.14

Instability Index59.91

Aliphatic Index 91.96

Aromaticity 0.0588

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1615.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2204.70

LogP -24.49

H-bond Donors 79.0

H-bond Acceptors 78.0

Rotatable Bonds 180.0

Heavy Atoms 369.0

Ring Count 3.0

Amide Bonds 52.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0422950 VERIFIED: NO

Provenance & Taxonomy

OrganismPriestia megaterium [Animal]

FamilyLantibiotic

Structure & Mods

Configthioether-cyclized lantibiotic scaffold [Cyclic]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLanthionine/methyllanthionine-type thioether crosslinks are implied by the lantibiotic annotation

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive

TargetGram-positive bacteria