Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length268 amino acids

Chemical FormulaC1276H2051N375O366S39

DescriptionStandard

        MFLKVVVVLLAVELSVAQSARQRVRPLDRKAGRKRFAPIFPRQCSEQFHGECMKSCGDLPQMVGLCPSGTICCENTGRKRFAPIFPRQCSEQFHGECMKSCGDLPQMVGLCPSGTICCENTGRKRFAPIFPRQCSEQFHGECMKSCGDLPQMVGLCPSGTICCENTGRKRFAPIFPRQCSEQFHGECMKSCGDLPQMVGLCPSGTICCENTGRKRFAPIFPRQCSEQFHGECMKSCGDLPQMVLVQLVARTLDIIHYKTVSTICDVLI
    

Molecular Weight29751.76 Da

Isoelectric Point (pI)8.64

Net Charge (pH 7.0)9.78

Net Charge (pH 7.4) 8.80

Charge Density (pH 7.0) 0.0365

GRAVY Index-0.12

Hydrophobic Moment 0.70

Boman Index-0.02

Instability Index59.66

Aliphatic Index 66.16

Aromaticity 0.0634

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 3240.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0256397 VERIFIED: NO

Provenance & Taxonomy

OrganismNematostella vectensis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence