‹ ›
MYP_044469
← PREVIOUS NEXT → BACK
Basic Information
Bombinin H-BO1
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
17 amino acids
C76H136N18O18
Standard
Sequence
IIGPVLGLVGKALGGLL
Physicochemical Analysis
1590.00 Da
8.75
0.76
0.55
0.0447
1.81
0.40
0.70
18.01
200.59
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
546.15
-1.40
18.0
19.0
52.0
112.0
1.0
16.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0157689 VERIFIED: YES
Provenance & Taxonomy
Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
161.1 μM
MIC
PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0207411 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0230377 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
Hep-G2
3.61 μM
IC50
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0324667 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer
SK-HEP-1
8.08 μM
IC50
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
RECORD: Rec_0346535 VERIFIED: YES
Provenance & Taxonomy
skin secretion of Oriental fire-bellied toad,Bombina orientalis [Animal]
Bombinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 29098406 PMID29098406 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29098406/
FIRST PREV 1 2 3 NEXT LAST
Showing 5 records on this page · Page 2 of 3