Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length196 amino acids

Chemical FormulaC973H1543N267O265S10

DescriptionStandard

        PTALRTVQEPMLLVAITEFVANSAAFTYFTAGALRRNISSNMLPKRFPLQLRTKNIGLFSPQLQERYPDQPMELHLSARQQPLLSCHPDALHGAVFGSAEAFVVLPNDTRVPAFLLDIDANMTGKPTITGNRLKGTMSLTGGAEPCLHHGPLCQPRAGLRGLPLLQVKRLETLLKFGLWLFGVPWANSECCPYPVL
    

Molecular Weight21541.94 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)5.36

Net Charge (pH 7.4) 4.95

Charge Density (pH 7.0) 0.0274

GRAVY Index0.03

Hydrophobic Moment 0.59

Boman Index0.11

Instability Index53.95

Aliphatic Index 95.10

Aromaticity 0.0765

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15720.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8362.69

LogP -101.73

H-bond Donors 288.0

H-bond Acceptors 285.0

Rotatable Bonds 686.0

Heavy Atoms 1515.0

Ring Count 41.0

Amide Bonds 212.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377734 VERIFIED: NO

Provenance & Taxonomy

OrganismAnhinga rufa [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria